PRESENTATION

Welcome to the Cancer Research Center of Lyon !

The Cancer Research Center of Lyon (CRCL, UMR Inserm 1052 CNRS 5286 - Centre Léon Bérard) is a research structure affiliated with the University Claude Bernard Lyon 1, the national health and research bodies (Inserm and CNRS), the Léon Bérard Comprehensive Cancer Centre (CLB) and with the Lyon University Hospitals (HCL) as clinical partners. The CRCL was officially created in January 2011 and its 5-year contract was recently renewed for the 2016-2020 period. It comprises 21 teams, totalling over 420 members, including 130 researchers and lecturers. The CRCL aims at increasing the international visibility and attractiveness of our research cluster, to facilitate the transfer of knowledge from fundamental cancer research to clinical applications in oncology, and to develop teaching and training in oncology. 

Managementthe CRCL is directed by Alain Puisieux, who is assisted by Patrick Mehlen and Charles Dumontet as Deputies, as well as the following committees: the Board of Directors, the Planning Committee (includes team leaders) and the Executive Committee. In addition, the CRCL can rely on an international Scientific Advisory Board, composed of independent researchers selected for their scientific expertise, their strategic vision of research and their international recognition. 

The CRCL is organized around three scientific departments focusing on the following research topics:
Signaling of tumoral escape (Management: Patrick Mehlen, Deputy: Laurent Bartholin)
Cancer cell plasticity (Management: Alain Puisieux, Deputy: Mathieu Gabut) 
Immunity, Virus, Inflammation (Co-Management: Christophe Caux & Fabien Zoulim) 

The teams of the CRCL can rely on state-of-the-art equipment (a cell sorting and cytometry platform, an imaging platform, a L3 laboratory, a tumor model laboratory, related technological platforms on the Lyon-Est site) and shared services (administrative unit, autoclave, etc...) to support their projects.

One of the main goals of the CRCL is to support the development of strong translational research to enable patients to rapidly benefit from breakthroughs in basic research. This bridge from "bench to bedside" was rendered possible due to the strong collaboration between clinicians and pathologists of the CLB and HCL and scientific teams of the CRCL, creating a continuity between basic research and clinical applications.

Several teams of the CRCL are involved in the DEVweCAN "Cancer, Development, targeted therapies" LabEx (Laboratoire d'Excellence) project, a new research structure created following  the national call for projects "Investissement d'Avenir" in 2010 (Director: P. Mehlen). In addition, some teams are associated with the LYRIC project (Dir. Jean-Yves Blay), a project that was successfully evaluated following the national Plan Cancer SIRIC (Integrated Cancer Reseach Cluster, Site de recherche intégrée en cancérologie") call of the INCa in 2010.

To increase its international visibility, the CRCL organized its first International Symposium at the Lyon Congress Centre on the 13-15th February 2013. The second edition took place in September 2015!

CENTRE DE RECHERCHE EN CANCEROLOGIE DE LYON (CRCL)
UMR INSERM 1052 CNRS 5286 - CENTRE LEON BERARD
Copyright 2011. CRCL
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